Baloxavir Marboxil
API’s Name：Baloxavir Marboxil
CAS No.：1985606-14-1
Indication：Influenza
Innovator：Shionogi & Roche
Specification：In House
Patent Expiry Date(The U.S)：Sep.21,2031
US DMF：36657
EU DMF：
CEP：
Only for R&D purpose
Product Detail
Intermediates
Code | CAS | Specification |
BLX-8 | 1370250-39-7 | In-House |
BLXM2 | 1370250-39-7 | In-House |
Background
Baloxavir marboxil is an antiviral drug and is an endonuclease inhibitor. In rats and monkeys, the blood concentration of the drug is lower than the minimum detection amount in a single oral administration of the drug. In preclinical influenza A and B infection models (including strains that are resistant to existing antiviral drugs), Baloxavir marboxil has a certain effect.
Chemical Properties
Storage | Store at -20°C |
M.Wt | 571.55 |
Cas No. | 1985606-14-1 |
Formula | C27H23F2N3O7S |
Synonyms | S-033188 |
Solubility | Soluble in DMSO |
Chemical Name | (((R)-12-((S)-7,8-difluoro-6,11-dihydrodibenzo[b,e]thiepin-11-yl)-6,8-dioxo-3,4,6,8,12,12a-hexahydro-1H-[1,4]oxazino[3,4-c]pyrido[2,1-f][1,2,4]triazin-7-yl)oxy)methyl methyl carbonate |
SDF | Download SDF |
Canonical SMILES | O=C1C=CN(N([C@]2(N(C3=O)CCOC2)[H])[C@H]4C5=CC=C(C(F)=C5CSC6=CC=CC=C46)F)C3=C1OCOC(OC)=O |
Shipping Condition | Evaluation sample solution: ship with blue ice. All other available sizes: ship with RT, or blue ice upon request. |
General tips | For obtaining a higher solubility, please warm the tube at 37°C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20°C for several months. |
Chemical structure
