Velpatasvir(PVP)

Velpatasvir(PVP)

API’s Name:Velpatasvir(PVP)

CAS No.:1377049-84-7

Indication:HCV

Innovator

Specification:In-House

US DMF:√

EU DMF

CEP

Only for R&D purpose

Product Detail

Intermediates

Code

CAS 

Specification

VLPM1

334769-80-1

In-House

VLPM2

1378388-16-9

In-House

VLP-5-Br

1438383-89-1

In-House

VLP-5

1378390-29-4

In-House

VLP-10

1378391-45-7

In-House

Foreign Names

Velpatasvirum (Latin)

Velpatasvir (German)

Velpatasvir (French)

Velpatasvir (Spanish)

Generic Names

Velpatasvir (OS: USAN)

GS-5816 (IS)

UNII-KCU0C7RS7Z (IS)

Multi-ingredient medications containing velpatasvir:sofosbuvir/velpatasvir systemic

Brand names: Epclusa

Drug class(es): antiviral combinations

Sofosbuvir/velpatasvir systemic is used in the treatment of:Hepatitis C

sofosbuvir/velpatasvir/voxilaprevir systemic

Brand names: Vosevi

Drug class(es): antiviral combinations

Sofosbuvir/velpatasvir/voxilaprevir systemic is used in the treatment of:Hepatitis C


Chemical Properties


StorageStore at -20°C
M.Wt883.0
Cas No.1377049-84-7
FormulaC49H54N8O8
SynonymsGS-5816
Solubility≥146.66mg/mL in DMSO (Need ultrasonic and warming); Insoluble in H2O
SDFDownload SDF
Canonical SMILESO=C(N1C[C@@H](COC)C[C@H]1C2=NC=C(C3=CC=C(C(C=C(C=CC4=C5N=C([C@H]6N(C([C@H](C(C)C)NC(OC)=O)=O)[C@@H](C)CC6)N4)C5=C7)=C7OC8)C8=C3)N2)[C@H](NC(OC)=O)C9=CC=CC=C9
Shipping ConditionEvaluation sample solution: ship with blue ice. All other available sizes: ship with RT, or blue ice upon request.
General tipsFor obtaining a higher solubility, please warm the tube at 37°C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20°C for several months.



Chemical structure



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